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2R1H

met-Trout IV hemoglobin at pH 6.3

Functional Information from GO Data
ChainGOidnamespacecontents
A0004601molecular_functionperoxidase activity
A0005344molecular_functionoxygen carrier activity
A0005833cellular_componenthemoglobin complex
A0015671biological_processoxygen transport
A0019825molecular_functionoxygen binding
A0020037molecular_functionheme binding
A0031720molecular_functionhaptoglobin binding
A0031838cellular_componenthaptoglobin-hemoglobin complex
A0042744biological_processhydrogen peroxide catabolic process
A0043177molecular_functionorganic acid binding
A0046872molecular_functionmetal ion binding
A0072562cellular_componentblood microparticle
A0098869biological_processcellular oxidant detoxification
B0004601molecular_functionperoxidase activity
B0005344molecular_functionoxygen carrier activity
B0005833cellular_componenthemoglobin complex
B0015671biological_processoxygen transport
B0019825molecular_functionoxygen binding
B0020037molecular_functionheme binding
B0031720molecular_functionhaptoglobin binding
B0031838cellular_componenthaptoglobin-hemoglobin complex
B0042744biological_processhydrogen peroxide catabolic process
B0043177molecular_functionorganic acid binding
B0046872molecular_functionmetal ion binding
B0072562cellular_componentblood microparticle
B0098869biological_processcellular oxidant detoxification
C0004601molecular_functionperoxidase activity
C0005344molecular_functionoxygen carrier activity
C0005833cellular_componenthemoglobin complex
C0015671biological_processoxygen transport
C0019825molecular_functionoxygen binding
C0020037molecular_functionheme binding
C0031720molecular_functionhaptoglobin binding
C0031838cellular_componenthaptoglobin-hemoglobin complex
C0042744biological_processhydrogen peroxide catabolic process
C0043177molecular_functionorganic acid binding
C0046872molecular_functionmetal ion binding
C0072562cellular_componentblood microparticle
C0098869biological_processcellular oxidant detoxification
D0004601molecular_functionperoxidase activity
D0005344molecular_functionoxygen carrier activity
D0005833cellular_componenthemoglobin complex
D0015671biological_processoxygen transport
D0019825molecular_functionoxygen binding
D0020037molecular_functionheme binding
D0031720molecular_functionhaptoglobin binding
D0031838cellular_componenthaptoglobin-hemoglobin complex
D0042744biological_processhydrogen peroxide catabolic process
D0043177molecular_functionorganic acid binding
D0046872molecular_functionmetal ion binding
D0072562cellular_componentblood microparticle
D0098869biological_processcellular oxidant detoxification
Functional Information from PDB Data
site_idAC3
Number of Residues17
DetailsBINDING SITE FOR RESIDUE HEM A 143
ChainResidue
ATYR42
AHIS88
ALEU92
AASN98
APHE99
ALEU102
ALEU137
AHOH155
AHOH169
APHE43
AHIS45
ATRP46
AHIS59
ATHR62
AILE67
ALEU84
ALEU87

site_idAC4
Number of Residues14
DetailsBINDING SITE FOR RESIDUE HEM B 148
ChainResidue
BHIS41
BPHE42
BPHE45
BHIS63
BMET91
BHIS92
BLEU96
BASN102
BPHE103
BLEU106
BLEU142
BHOH2785
BHOH2862
DLYS95

site_idAC5
Number of Residues15
DetailsBINDING SITE FOR RESIDUE HEM C 143
ChainResidue
CTYR42
CPHE43
CHIS45
CTRP46
CHIS59
CTHR62
CLEU87
CHIS88
CLEU92
CASN98
CPHE99
CLEU102
CLEU137
CHOH2782
CHOH2836

site_idAC6
Number of Residues13
DetailsBINDING SITE FOR RESIDUE HEM D 148
ChainResidue
DTHR38
DHIS41
DPHE42
DPHE45
DHIS63
DLEU88
DMET91
DHIS92
DLEU96
DASN102
DPHE103
DLEU106
DLEU142

site_idAC7
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 2775
ChainResidue
BALA107
BASP108
BGLN132
BALA136
BHOH2791

site_idAC8
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO D 2775
ChainResidue
CHOH2786
DARG104
DALA107
DASP108
DGLN132
DALA136
DHOH2793

site_idAC9
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO C 2775
ChainResidue
CTRP46
CHIS59
CTHR62
CHOH2787

site_idBC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 2776
ChainResidue
BLEU78
BASP79
BASP80
BILE81
BLYS82

site_idBC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO C 2776
ChainResidue
CGLU26
CGLN27
CSER30
CHOH2783

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: distal binding residue
ChainResidueDetails
BHIS63
DHIS63

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: proximal binding residue
ChainResidueDetails
BHIS92
DHIS92

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: N-acetylserine => ECO:0000269|PubMed:2706274
ChainResidueDetails
ASER1
CSER1

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PDB entries from 2025-06-18

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