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2PJY

Structural basis for cooperative assembly of the TGF-beta signaling complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0008083molecular_functiongrowth factor activity
B0005026molecular_functiontransforming growth factor beta receptor activity, type II
B0005524molecular_functionATP binding
B0006468biological_processprotein phosphorylation
B0016020cellular_componentmembrane
B0046872molecular_functionmetal ion binding
C0004675molecular_functiontransmembrane receptor protein serine/threonine kinase activity
C0016020cellular_componentmembrane
Functional Information from PROSITE/UniProt
site_idPS00250
Number of Residues16
DetailsTGF_BETA_1 TGF-beta family signature. VhePkgYyanfCsGpC
ChainResidueDetails
AVAL33-CYS48

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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