Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 777 |
| Chain | Residue |
| A | HOH1 |
| A | HOH2 |
| A | HOH3 |
| A | HOH4 |
| A | HOH5 |
| A | ASP564 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 777 |
| Chain | Residue |
| B | HOH14 |
| B | HOH15 |
| B | ASP564 |
| B | HOH11 |
| B | HOH12 |
| B | HOH13 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 35G A 778 |
| Chain | Residue |
| A | HOH1 |
| A | HOH7 |
| A | HOH9 |
| A | HOH237 |
| A | HOH255 |
| A | TYR524 |
| A | HIS525 |
| A | LEU635 |
| A | LEU675 |
| A | ILE692 |
| A | TYR693 |
| A | MET713 |
| A | GLN726 |
| A | PHE729 |
| B | LEU706 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 35G A 779 |
| Chain | Residue |
| A | HOH130 |
| A | HOH227 |
| A | LEU654 |
| A | ASN655 |
| A | LEU656 |
| A | ASN657 |
| A | ILE744 |
| A | PRO746 |
| A | 35G780 |
| B | VAL466 |
| B | ARG467 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 35G A 780 |
| Chain | Residue |
| A | HOH62 |
| A | HOH81 |
| A | HOH122 |
| A | HOH164 |
| A | HOH227 |
| A | HOH240 |
| A | HOH242 |
| A | HOH270 |
| A | ILE450 |
| A | THR452 |
| A | SER453 |
| A | GLN743 |
| A | PRO746 |
| A | 35G779 |
| B | HOH181 |
| B | ARG467 |
| B | LYS470 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGfsNsY |
| Chain | Residue | Details |
| A | HIS563-TYR574 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 317 |
| Details | Domain: {"description":"PDEase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01192","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17389385","evidenceCode":"ECO:0000269"}]} |
