Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE 242 A 503 |
Chain | Residue |
A | VAL259 |
A | ILE314 |
A | THR316 |
A | GLU317 |
A | TYR318 |
A | MET319 |
A | HIS362 |
A | ILE380 |
A | ALA381 |
A | ASP382 |
A | PHE383 |
A | ALA271 |
A | HOH630 |
A | VAL272 |
A | LYS273 |
A | GLU288 |
A | MET292 |
A | LEU295 |
A | LEU300 |
A | VAL301 |
site_id | AC2 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE 242 B 503 |
Chain | Residue |
B | VAL259 |
B | ALA271 |
B | LYS273 |
B | GLU288 |
B | MET292 |
B | LEU300 |
B | VAL301 |
B | ILE314 |
B | THR316 |
B | GLU317 |
B | TYR318 |
B | MET319 |
B | GLY322 |
B | TYR360 |
B | LEU371 |
B | ILE380 |
B | ALA381 |
B | ASP382 |
B | PHE383 |
B | ILE389 |
B | HOH518 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 23 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGAGQFGEVWmGyynghtk...........VAVK |
Chain | Residue | Details |
A | LEU251-LYS273 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YIHrDLRAANILV |
Chain | Residue | Details |
A | TYR360-VAL372 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP364 | |
B | ASP364 | |
Chain | Residue | Details |
A | LEU251 | |
A | LYS273 | |
B | LEU251 | |
B | LYS273 | |
Chain | Residue | Details |
A | TYR394 | |
B | TYR394 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ALA368 | |
A | ASP364 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ALA368 | |
B | ASP364 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP364 | |
A | ARG366 | |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ASP364 | |
B | ARG366 | |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP364 | |
A | ARG366 | |
A | ASN369 | |
site_id | CSA6 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ASP364 | |
B | ARG366 | |
B | ASN369 | |