Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0044174 | cellular_component | host cell endosome |
| A | 0055036 | cellular_component | virion membrane |
| A | 0072494 | cellular_component | host multivesicular body |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0044174 | cellular_component | host cell endosome |
| B | 0055036 | cellular_component | virion membrane |
| B | 0072494 | cellular_component | host multivesicular body |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 401 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH461 |
| B | ARG41 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 402 |
| Chain | Residue |
| B | THR74 |
| B | ASN88 |
| B | HOH413 |
| B | HOH490 |
| B | HOH530 |
| site_id | AC3 |
| Number of Residues | 39 |
| Details | BINDING SITE FOR RESIDUE TPV A 403 |
| Chain | Residue |
| A | ARG8 |
| A | LEU23 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | VAL32 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | VAL50 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | GOL405 |
| A | HOH428 |
| A | HOH588 |
| A | HOH589 |
| A | HOH590 |
| B | ARG8 |
| B | LEU23 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | VAL32 |
| B | ILE47 |
| B | GLY48 |
| B | GLY49 |
| B | VAL50 |
| B | PRO81 |
| B | VAL82 |
| B | GOL404 |
| B | HOH420 |
| B | HOH448 |
| B | HOH535 |
| B | HOH597 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 404 |
| Chain | Residue |
| A | TPV403 |
| B | ALA28 |
| B | ASP29 |
| B | ILE47 |
| B | GLY48 |
| B | HOH443 |
| B | HOH535 |
| B | HOH597 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 405 |
| Chain | Residue |
| A | ALA28 |
| A | ASP29 |
| A | GLY48 |
| A | TPV403 |
| A | HOH474 |
| A | HOH588 |
| A | HOH590 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | THR26 | |
| B | THR26 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PRO1 | |
| B | PRO1 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| B | ASP25 | |
| B | THR26 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
