2MUT

Solution structure of the F231L mutant ERCC1-XPF dimerization region

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0005634	cellular_component	nucleus
A	0006281	biological_process	DNA repair

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	77
Details	Region: {"description":"HhH2, dimerization with ERCC4/XPF","evidences":[{"source":"PubMed","id":"16338413","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	68
Details	Region: {"description":"HhH2, dimerization with ERCC1","evidences":[{"source":"PubMed","id":"16076955","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"32034146","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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