Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2JLX

Dengue virus 4 NS3 helicase in complex with ssRNA and ADP-Vanadate

Functional Information from GO Data
ChainGOidnamespacecontents
A0004386molecular_functionhelicase activity
A0005524molecular_functionATP binding
B0004386molecular_functionhelicase activity
B0005524molecular_functionATP binding
Functional Information from PDB Data
site_idAC1
Number of Residues14
DetailsBINDING SITE FOR RESIDUE ADP A 1619
ChainResidue
AGLY196
AARG418
AARG463
AVO41620
AMN1621
AHOH2198
AALA197
AGLY198
ALYS199
ATHR200
ALYS201
AGLU233
AASN329
AASN416

site_idAC2
Number of Residues14
DetailsBINDING SITE FOR RESIDUE ADP B 1619
ChainResidue
BGLY196
BALA197
BGLY198
BLYS199
BTHR200
BLYS201
BASN329
BASN416
BARG418
BARG463
BVO41620
BMN1621
BCL1622
BHOH2170

site_idAC3
Number of Residues14
DetailsBINDING SITE FOR RESIDUE VO4 A 1620
ChainResidue
APRO195
AGLY196
ALYS199
AGLU285
AALA316
AGLY414
AGLN456
AARG460
AARG463
AADP1619
AMN1621
AHOH2042
AHOH2197
AHOH2198

site_idAC4
Number of Residues15
DetailsBINDING SITE FOR RESIDUE VO4 B 1620
ChainResidue
BPRO195
BGLY196
BLYS199
BGLU285
BALA316
BGLY414
BGLN456
BARG460
BARG463
BADP1619
BMN1621
BHOH2028
BHOH2170
BHOH2171
BHOH2172

site_idAC5
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MN A 1621
ChainResidue
ATHR200
AGLU285
AADP1619
AVO41620
AHOH2196
AHOH2197
AHOH2198

site_idAC6
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MN B 1621
ChainResidue
BTHR200
BGLU285
BADP1619
BVO41620
BHOH2170
BHOH2171
BHOH2172

site_idAC7
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL B 1622
ChainResidue
BASN416
BARG418
BARG463
BADP1619
BHOH2106

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00541
ChainResidueDetails
ALEU193
BLEU193

site_idSWS_FT_FI2
Number of Residues4
DetailsSITE: Involved in NS3 ATPase and RTPase activities => ECO:0000250|UniProtKB:P14335
ChainResidueDetails
AARG457
AARG460
BARG457
BARG460

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Cleavage; by autolysis => ECO:0000250|UniProtKB:P29990
ChainResidueDetails
ALYS618
BLYS618

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: N6-acetyllysine; by host => ECO:0000250|UniProtKB:Q32ZE1
ChainResidueDetails
ALYS388
BLYS388

227111

PDB entries from 2024-11-06

PDB statisticsPDBj update infoContact PDBjnumon