2HP4
Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | ARG4 |
| A | HOH513 |
| A | HOH529 |
| B | PRO7 |
| B | ARG10 |
| B | LYS21 |
| B | HOH476 |
| B | HOH515 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | ARG10 |
| A | LYS21 |
| A | HOH453 |
| A | HOH455 |
| A | HOH495 |
| A | HOH512 |
| A | HOH521 |
| A | HOH545 |
| B | ARG4 |
| A | PRO7 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 303 |
| Chain | Residue |
| A | HOH472 |
| B | ASN53 |
| B | GLN54 |
| B | ASN55 |
| B | HOH423 |
| B | HOH451 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | ASN53 |
| A | GLN54 |
| A | ASN55 |
| A | HOH414 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 305 |
| Chain | Residue |
| A | GLN23 |
| A | GLY74 |
| A | ASP75 |
| A | THR76 |
| B | GLN23 |
| B | ASP75 |
| B | THR76 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 401 |
| Chain | Residue |
| A | SER1 |
| A | HIS106 |
| A | HOH427 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 402 |
| Chain | Residue |
| B | SER1 |
| B | HIS106 |
| B | HOH426 |
| B | HOH491 |
| B | HOH533 |
| B | HOH538 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | PHE37 |
| A | THR47 |
| A | LEU49 |
| A | PHE68 |
| A | ASN88 |
| A | TYR92 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 404 |
| Chain | Residue |
| B | LEU49 |
| B | ASN88 |
| B | TYR92 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 226 |
| Details | Domain: {"description":"Ig-like V-type"} |
| Chain | Residue | Details |
