2HL5

Crystal structure of the C-terminal domain of human EB1 in complex with the A49M mutant CAP-Gly domain of human Dynactin-1 (p150-Glued)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008017	molecular_function	microtubule binding
B	0008017	molecular_function	microtubule binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 235

Chain	Residue
D	ARG32
D	PHE97

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Functional Information from PROSITE/UniProt

site_id	PS00845
Number of Residues	32
Details	CAP_GLY_1 CAP-Gly domain signature. Gmtlfatgk..WvGVilDeak....GKNdGTvqGrkYF

Chain	Residue	Details
C	GLY48-PHE79

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Region: {"description":"Interaction with APC","evidences":[{"source":"PubMed","id":"17293347","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	44
Details	Region: {"description":"APC-binding","evidences":[{"source":"PubMed","id":"14514668","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23001180","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	84
Details	Domain: {"description":"CAP-Gly","evidences":[{"source":"PROSITE-ProRule","id":"PRU00045","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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