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2HCD

Crystal structure of the ligand binding domain of the Vitamin D nuclear receptor in complex with Gemini and a coactivator peptide

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues17
DetailsBINDING SITE FOR RESIDUE BIV A 525
ChainResidue
ATYR175
ASER306
ATRP314
ACYS316
AHIS333
ALEU337
ALEU419
AHIS423
AGLN426
ATYR179
ALEU258
ALEU261
AVAL262
ASER265
AMET300
AARG302
ASER303

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
BSER698
ASER265
AARG302
ASER306
AHIS333
AHIS423

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PDB entries from 2024-11-06

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