2FXS
Yeast HSP82 in complex with the novel HSP90 Inhibitor Radamide
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE RDA A 1001 |
| Chain | Residue |
| A | ASN37 |
| A | PHE124 |
| A | THR171 |
| A | LEU173 |
| A | HOH1094 |
| A | HOH1095 |
| A | HOH1180 |
| A | HOH1220 |
| A | HOH1221 |
| A | HOH1230 |
| A | HOH1245 |
| A | ALA41 |
| A | LYS44 |
| A | ASP79 |
| A | ILE82 |
| A | MET84 |
| A | ASN91 |
| A | ASN92 |
| A | LYS98 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 301 |
| Chain | Residue |
| A | LYS73 |
| A | ASP132 |
| A | LEU177 |
| A | LYS178 |
| A | ASP179 |
| A | HOH1135 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 302 |
| Chain | Residue |
| A | LYS54 |
| A | GLN55 |
| A | THR58 |
| A | ASN141 |
| A | HOH1103 |
| A | HOH1259 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 303 |
| Chain | Residue |
| A | SER25 |
| A | GLU183 |
| A | ARG189 |
| A | HOH1032 |
| A | HOH1033 |
| A | HOH1190 |
| A | HOH1218 |
| A | HOH1219 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 304 |
| Chain | Residue |
| A | GLU149 |
| A | ASN151 |
| A | SER155 |
| A | PHE156 |
| A | THR157 |
| A | HOH1051 |
| A | HOH1184 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 305 |
| Chain | Residue |
| A | LYS69 |
| A | GLN72 |
| A | ARG174 |
| A | HOH1077 |
| A | HOH1174 |
Functional Information from PROSITE/UniProt
| site_id | PS00298 |
| Number of Residues | 10 |
| Details | HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE |
| Chain | Residue | Details |
| A | TYR24-GLU33 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16625188","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2CG9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16625188","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9230303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AM1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AMW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WEP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
