1YTU
Structural basis for 5'-end-specific recognition of the guide RNA strand by the A. fulgidus PIWI protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 428 |
| Chain | Residue |
| A | GLN159 |
| A | LEU427 |
| C | A1 |
| C | A3 |
| C | HOH57 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 428 |
| Chain | Residue |
| E | HOH17 |
| B | GLN159 |
| B | LEU427 |
| E | A1 |
| E | A3 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Region: {"description":"Binds 5'-phosphorylated end of guide DNA","evidences":[{"source":"PubMed","id":"19187762","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2W42","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Region: {"description":"Binds target DNA","evidences":[{"source":"PubMed","id":"19187762","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2W42","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Region: {"description":"Binds guide DNA","evidences":[{"source":"PubMed","id":"19187762","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2W42","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1YTU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BGG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2W42","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
