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1YKB

Crystal Structure of Insect Cell Expressed IL-22

Functional Information from GO Data
ChainGOidnamespacecontents
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006953biological_processacute-phase response
A0006954biological_processinflammatory response
A0007165biological_processsignal transduction
A0045518molecular_functioninterleukin-22 receptor binding
A0050728biological_processnegative regulation of inflammatory response
A0051384biological_processresponse to glucocorticoid
B0005125molecular_functioncytokine activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0006953biological_processacute-phase response
B0006954biological_processinflammatory response
B0007165biological_processsignal transduction
B0045518molecular_functioninterleukin-22 receptor binding
B0050728biological_processnegative regulation of inflammatory response
B0051384biological_processresponse to glucocorticoid
C0005125molecular_functioncytokine activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0006953biological_processacute-phase response
C0006954biological_processinflammatory response
C0007165biological_processsignal transduction
C0045518molecular_functioninterleukin-22 receptor binding
C0050728biological_processnegative regulation of inflammatory response
C0051384biological_processresponse to glucocorticoid
D0005125molecular_functioncytokine activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0006953biological_processacute-phase response
D0006954biological_processinflammatory response
D0007165biological_processsignal transduction
D0045518molecular_functioninterleukin-22 receptor binding
D0050728biological_processnegative regulation of inflammatory response
D0051384biological_processresponse to glucocorticoid
E0005125molecular_functioncytokine activity
E0005515molecular_functionprotein binding
E0005576cellular_componentextracellular region
E0005615cellular_componentextracellular space
E0006953biological_processacute-phase response
E0006954biological_processinflammatory response
E0007165biological_processsignal transduction
E0045518molecular_functioninterleukin-22 receptor binding
E0050728biological_processnegative regulation of inflammatory response
E0051384biological_processresponse to glucocorticoid
F0005125molecular_functioncytokine activity
F0005515molecular_functionprotein binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0006953biological_processacute-phase response
F0006954biological_processinflammatory response
F0007165biological_processsignal transduction
F0045518molecular_functioninterleukin-22 receptor binding
F0050728biological_processnegative regulation of inflammatory response
F0051384biological_processresponse to glucocorticoid
Functional Information from PROSITE/UniProt
site_idPS00520
Number of Residues21
DetailsINTERLEUKIN_10 Interleukin-10 family signature. SmserCYlmkqVLnFTLeEVL
ChainResidueDetails
ASER84-LEU104

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15983417
ChainResidueDetails
AASN54
EASN97
FASN54
FASN97
AASN97
BASN54
BASN97
CASN54
CASN97
DASN54
DASN97
EASN54

site_idSWS_FT_FI2
Number of Residues6
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN68
BASN68
CASN68
DASN68
EASN68
FASN68

223790

PDB entries from 2024-08-14

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