1UPT

Structure of a complex of the golgin-245 GRIP domain with Arl1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0000166	molecular_function	nucleotide binding
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005802	cellular_component	trans-Golgi network
A	0005829	cellular_component	cytosol
A	0006886	biological_process	intracellular protein transport
A	0007030	biological_process	Golgi organization
A	0008047	molecular_function	enzyme activator activity
A	0009404	biological_process	toxin metabolic process
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
A	0019904	molecular_function	protein domain specific binding
A	0032588	cellular_component	trans-Golgi network membrane
A	0034067	biological_process	protein localization to Golgi apparatus
A	0042147	biological_process	retrograde transport, endosome to Golgi
A	0046872	molecular_function	metal ion binding
A	1990583	molecular_function	phospholipase D activator activity
C	0000139	cellular_component	Golgi membrane
C	0000166	molecular_function	nucleotide binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005794	cellular_component	Golgi apparatus
C	0005802	cellular_component	trans-Golgi network
C	0005829	cellular_component	cytosol
C	0006886	biological_process	intracellular protein transport
C	0007030	biological_process	Golgi organization
C	0008047	molecular_function	enzyme activator activity
C	0009404	biological_process	toxin metabolic process
C	0016020	cellular_component	membrane
C	0016192	biological_process	vesicle-mediated transport
C	0019904	molecular_function	protein domain specific binding
C	0032588	cellular_component	trans-Golgi network membrane
C	0034067	biological_process	protein localization to Golgi apparatus
C	0042147	biological_process	retrograde transport, endosome to Golgi
C	0046872	molecular_function	metal ion binding
C	1990583	molecular_function	phospholipase D activator activity
E	0000139	cellular_component	Golgi membrane
E	0000166	molecular_function	nucleotide binding
E	0003924	molecular_function	GTPase activity
E	0005515	molecular_function	protein binding
E	0005525	molecular_function	GTP binding
E	0005737	cellular_component	cytoplasm
E	0005794	cellular_component	Golgi apparatus
E	0005802	cellular_component	trans-Golgi network
E	0005829	cellular_component	cytosol
E	0006886	biological_process	intracellular protein transport
E	0007030	biological_process	Golgi organization
E	0008047	molecular_function	enzyme activator activity
E	0009404	biological_process	toxin metabolic process
E	0016020	cellular_component	membrane
E	0016192	biological_process	vesicle-mediated transport
E	0019904	molecular_function	protein domain specific binding
E	0032588	cellular_component	trans-Golgi network membrane
E	0034067	biological_process	protein localization to Golgi apparatus
E	0042147	biological_process	retrograde transport, endosome to Golgi
E	0046872	molecular_function	metal ion binding
E	1990583	molecular_function	phospholipase D activator activity
G	0000139	cellular_component	Golgi membrane
G	0000166	molecular_function	nucleotide binding
G	0003924	molecular_function	GTPase activity
G	0005515	molecular_function	protein binding
G	0005525	molecular_function	GTP binding
G	0005737	cellular_component	cytoplasm
G	0005794	cellular_component	Golgi apparatus
G	0005802	cellular_component	trans-Golgi network
G	0005829	cellular_component	cytosol
G	0006886	biological_process	intracellular protein transport
G	0007030	biological_process	Golgi organization
G	0008047	molecular_function	enzyme activator activity
G	0009404	biological_process	toxin metabolic process
G	0016020	cellular_component	membrane
G	0016192	biological_process	vesicle-mediated transport
G	0019904	molecular_function	protein domain specific binding
G	0032588	cellular_component	trans-Golgi network membrane
G	0034067	biological_process	protein localization to Golgi apparatus
G	0042147	biological_process	retrograde transport, endosome to Golgi
G	0046872	molecular_function	metal ion binding
G	1990583	molecular_function	phospholipase D activator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A1183

Chain	Residue
A	THR31
A	THR48
A	GTP1182
A	HOH2003
A	HOH2007

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C1182

Chain	Residue
C	HOH2032
C	THR31
C	THR48
C	GTP1181
C	HOH2013

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG E1182

Chain	Residue
E	THR31
E	THR48
E	GTP1181
E	HOH2032
E	HOH2093

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG G1182

Chain	Residue
G	THR31
G	THR48
G	GTP1181
G	HOH2005
G	HOH2053

---

site_id	AC5
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GTP A1182

Chain	Residue
A	ASP26
A	GLY27
A	ALA28
A	GLY29
A	LYS30
A	THR31
A	THR32
A	THR45
A	THR48
A	GLY70
A	ASN126
A	LYS127
A	ASP129
A	MSE130
A	SER159
A	ALA160
A	THR161
A	MG1183
A	HOH2003
A	HOH2007
A	HOH2048
A	HOH2050

---

site_id	AC6
Number of Residues	24
Details	BINDING SITE FOR RESIDUE GTP C1181

Chain	Residue
C	ASP26
C	GLY27
C	ALA28
C	GLY29
C	LYS30
C	THR31
C	THR32
C	THR45
C	THR48
C	GLY70
C	ASN126
C	LYS127
C	ASP129
C	MSE130
C	SER159
C	ALA160
C	THR161
C	MG1182
C	HOH2008
C	HOH2013
C	HOH2031
C	HOH2032
C	HOH2033
C	HOH2034

---

site_id	AC7
Number of Residues	25
Details	BINDING SITE FOR RESIDUE GTP E1181

Chain	Residue
E	ASP26
E	GLY27
E	ALA28
E	GLY29
E	LYS30
E	THR31
E	THR32
E	THR45
E	THR48
E	GLY69
E	GLY70
E	ASN126
E	LYS127
E	ASP129
E	SER159
E	ALA160
E	THR161
E	MG1182
E	HOH2012
E	HOH2032
E	HOH2092
E	HOH2093
E	HOH2094
E	HOH2095
E	HOH2096

---

site_id	AC8
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GTP G1181

Chain	Residue
G	THR48
G	GLY70
G	ASN126
G	LYS127
G	ASP129
G	MSE130
G	SER159
G	ALA160
G	THR161
G	MG1182
G	HOH2005
G	HOH2011
G	HOH2052
G	HOH2053
G	HOH2054
G	ASP26
G	GLY27
G	ALA28
G	GLY29
G	LYS30
G	THR31
G	THR32
G	THR45

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14580338","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27373159","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27436755","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14580338","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	LEU71

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	LEU71

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
E	LEU71

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
G	LEU71

---