1UOM
The Structure of Estrogen Receptor in Complex with a Selective and Potent Tetrahydroisochiolin Ligand.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PTI A1547 |
| Chain | Residue |
| A | MET343 |
| A | ILE424 |
| A | GLY521 |
| A | HIS524 |
| A | LEU525 |
| A | LEU539 |
| A | HOH2025 |
| A | LEU346 |
| A | THR347 |
| A | ALA350 |
| A | ASP351 |
| A | GLU353 |
| A | TRP383 |
| A | LEU387 |
| A | ARG394 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE |
| Chain | Residue | Details |
| A | GLU353 | |
| A | ARG394 | |
| A | HIS524 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 |
| Chain | Residue | Details |
| A | TYR537 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS447 |
