1TF6

CO-CRYSTAL STRUCTURE OF XENOPUS TFIIIA ZINC FINGER DOMAIN BOUND TO THE 5S RIBOSOMAL RNA GENE INTERNAL CONTROL REGION

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	CYS15
A	CYS20
A	HIS33
A	HIS37

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 202

Chain	Residue
A	CYS45
A	CYS50
A	HIS63
A	HIS67

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 203

Chain	Residue
A	CYS75
A	SER77
A	CYS80
A	HIS93
A	HIS98

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 204

Chain	Residue
A	CYS107
A	CYS112
A	HIS125
A	HIS129

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 205

Chain	Residue
A	CYS137
A	CYS142
A	HIS155
A	HIS159

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 206

Chain	Residue
A	CYS164
A	CYS170
A	HIS183
A	HIS188

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 201

Chain	Residue
D	CYS15
D	CYS20
D	HIS33
D	HIS37

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 202

Chain	Residue
D	CYS45
D	CYS50
D	HIS63
D	HIS67

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 203

Chain	Residue
D	CYS75
D	SER77
D	CYS80
D	HIS93
D	HIS98

---

site_id	AN1
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
A	CYS15
A	CYS20
A	HIS33
A	HIS37

---

site_id	AN2
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
A	CYS45
A	CYS50
A	HIS63
A	HIS67

---

site_id	AN3
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
A	CYS80
A	HIS93
A	HIS98
A	CYS75

---

site_id	AN4
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
A	CYS107
A	CYS112
A	HIS125
A	HIS129

---

site_id	AN5
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
A	CYS137
A	CYS142
A	HIS155
A	HIS159

---

site_id	AN6
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
A	CYS164
A	CYS170
A	HIS183
A	HIS188

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 204

Chain	Residue
D	CYS107
D	CYS112
D	HIS125
D	HIS129

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 205

Chain	Residue
D	CYS137
D	CYS142
D	HIS155
D	HIS159

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 206

Chain	Residue
D	CYS164
D	CYS170
D	HIS183
D	HIS188

---

site_id	DN1
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
D	CYS15
D	CYS20
D	HIS33
D	HIS37

---

site_id	DN2
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
D	CYS45
D	CYS50
D	HIS63
D	HIS67

---

site_id	DN3
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
D	CYS75
D	CYS80
D	HIS93
D	HIS98

---

site_id	DN4
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
D	CYS107
D	CYS112
D	HIS125
D	HIS129

---

site_id	DN5
Number of Residues	4
Details	ZN-BINDING SITE.

Chain	Residue
D	CYS137
D	CYS142
D	HIS155
D	HIS159

---

site_id	DN6
Number of Residues	4
Details	'ZN-BINDING

Chain	Residue
D	CYS164
D	CYS170
D	HIS183
D	HIS188

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CsfadCgaaYnknwklqaHlck..H

Chain	Residue	Details
A	CYS15-HIS37
A	CYS45-HIS67
A	CYS75-HIS98
A	CYS107-HIS129
A	CYS137-HIS159

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	ZN_FING: C2H2-type 1 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR13-HIS37
D	TYR13-HIS37

---

site_id	SWS_FT_FI2
Number of Residues	48
Details	ZN_FING: C2H2-type 2 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	PHE43-HIS67
D	PHE43-HIS67

---

site_id	SWS_FT_FI3
Number of Residues	50
Details	ZN_FING: C2H2-type 3 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	PHE73-HIS98
D	PHE73-HIS98

---

site_id	SWS_FT_FI4
Number of Residues	48
Details	ZN_FING: C2H2-type 4 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR105-HIS129
D	TYR105-HIS129

---

site_id	SWS_FT_FI5
Number of Residues	48
Details	ZN_FING: C2H2-type 5 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR135-HIS159
D	TYR135-HIS159

---

site_id	SWS_FT_FI6
Number of Residues	52
Details	ZN_FING: C2H2-type 6 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR162-HIS188
D	TYR162-HIS188

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	MOD_RES: Phosphoserine; by CK2 => ECO:0000269|PubMed:11853545

Chain	Residue	Details
A	SER16
D	SER16

---