1T08

Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007155	biological_process	cell adhesion
A	0045296	molecular_function	cadherin binding
B	0008013	molecular_function	beta-catenin binding
B	0030178	biological_process	negative regulation of Wnt signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine; by CDK5 => ECO:0000269|PubMed:17009320, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER191

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine; by CDK5 => ECO:0000269|PubMed:17009320

Chain	Residue	Details
A	SER246

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphotyrosine; by PTK6 => ECO:0000269|PubMed:20026641

Chain	Residue	Details
A	TYR331

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphotyrosine; by SRC and PTK6 => ECO:0000269|PubMed:22056988, ECO:0000305|PubMed:20026641

Chain	Residue	Details
A	TYR333

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER552

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18220336

Chain	Residue	Details
A	THR556

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: S-nitrosocysteine => ECO:0000250|UniProtKB:Q02248

Chain	Residue	Details
A	CYS619

---