Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 600 |
| Chain | Residue |
| A | ASP110 |
| A | VAL111 |
| A | ASP185 |
| A | TNV823 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | ASP443 |
| A | ASP498 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TNV A 823 |
| Chain | Residue |
| A | VAL111 |
| A | GLY112 |
| A | ASP113 |
| A | ALA114 |
| A | GLN151 |
| A | ASP185 |
| A | LYS219 |
| A | MG600 |
| P | DDG822 |
| T | DT705 |
| T | DC706 |
| A | LYS65 |
| A | ARG72 |
| A | ASP110 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 824 |
| Chain | Residue |
| A | LYS101 |
| A | LYS103 |
| A | VAL106 |
| A | TYR188 |
| A | HIS235 |
| A | PRO236 |
| A | TYR318 |
| A | HOH827 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 825 |
| Chain | Residue |
| A | GLU328 |
| A | GLN340 |
| A | TYR342 |
| A | PRO345 |
| A | GOL826 |
| A | HOH829 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 826 |
| Chain | Residue |
| A | GLN330 |
| A | GLN340 |
| A | GOL825 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 438 |
| Chain | Residue |
| B | ASP76 |
| B | ARG78 |
| B | GLU79 |
| B | LYS82 |
| B | GLU413 |
| B | GOL439 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL B 439 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 190 |
| Details | Domain: {"description":"Reverse transcriptase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00405","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Region: {"description":"RT 'primer grip'"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Motif: {"description":"Tryptophan repeat motif"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for RT p66/p51 heterodimerization"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by viral protease; partial"} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 16 |
| Details | Motif: {"description":"Tryptophan repeat motif","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for RT p66/p51 heterodimerization","evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | |
| Details | M-CSA 175 |
