1SB7
Crystal structure of the E.coli pseudouridine synthase TruD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001522 | biological_process | pseudouridine synthesis |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006396 | biological_process | RNA processing |
| A | 0008033 | biological_process | tRNA processing |
| A | 0009451 | biological_process | RNA modification |
| A | 0009982 | molecular_function | pseudouridine synthase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0031119 | biological_process | tRNA pseudouridine synthesis |
| A | 0106029 | molecular_function | tRNA pseudouridine synthase activity |
| A | 0140098 | molecular_function | catalytic activity, acting on RNA |
| A | 0160150 | molecular_function | tRNA pseudouridine(13) synthase activity |
| B | 0001522 | biological_process | pseudouridine synthesis |
| B | 0003723 | molecular_function | RNA binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006396 | biological_process | RNA processing |
| B | 0008033 | biological_process | tRNA processing |
| B | 0009451 | biological_process | RNA modification |
| B | 0009982 | molecular_function | pseudouridine synthase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0031119 | biological_process | tRNA pseudouridine synthesis |
| B | 0106029 | molecular_function | tRNA pseudouridine synthase activity |
| B | 0140098 | molecular_function | catalytic activity, acting on RNA |
| B | 0160150 | molecular_function | tRNA pseudouridine(13) synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1301 |
| Chain | Residue |
| B | LEU126 |
| B | ASN129 |
| B | ALA326 |
| B | GLY327 |
| B | HOH1156 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1201 |
| Chain | Residue |
| B | ALA297 |
| B | ARG298 |
| B | HOH961 |
| A | GLY12 |
| A | LYS13 |
| B | GLY231 |
| B | TRP233 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1202 |
| Chain | Residue |
| A | GLY231 |
| A | TRP233 |
| A | ALA297 |
| A | ARG298 |
| A | HOH968 |
| B | GLY12 |
| B | LYS13 |
| B | ARG147 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1203 |
| Chain | Residue |
| A | PHE27 |
| A | PHE131 |
| A | PHE329 |
| A | ALA330 |
| A | THR331 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1204 |
| Chain | Residue |
| B | ASP32 |
| B | LYS127 |
| B | GLN306 |
| B | GLN307 |
| B | HOH1154 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 1205 |
| Chain | Residue |
| B | SER309 |
| B | TRP310 |
| B | HOH1063 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL B 1206 |
| Chain | Residue |
| B | TRP313 |
Functional Information from PROSITE/UniProt
| site_id | PS01268 |
| Number of Residues | 14 |
| Details | UPF0024 Uncharacterized protein family UPF0024 signature. GqKDKhAVTeQwLC |
| Chain | Residue | Details |
| A | GLY77-CYS90 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255 |
| Chain | Residue | Details |
| A | GLU31 | |
| B | GLU31 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:19664587 |
| Chain | Residue | Details |
| A | ASP80 | |
| B | ASP80 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE27 | |
| A | PHE329 | |
| B | PHE27 | |
| B | PHE329 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | ASN129 | |
| B | ASN129 |
