Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0005634 | cellular_component | nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0051726 | biological_process | regulation of cell cycle |
| C | 0005634 | cellular_component | nucleus |
| C | 0043066 | biological_process | negative regulation of apoptotic process |
| C | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE IMZ A 110 |
| Chain | Residue |
| A | HOH10 |
| A | HIS96 |
| C | HOH9 |
| C | LEU54 |
| C | HIS96 |
| C | TYR100 |
| C | IMZ110 |
| A | HOH20 |
| A | LEU54 |
| A | GLY58 |
| A | ILE61 |
| A | MET62 |
| A | GLN72 |
| A | HIS73 |
| A | VAL93 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE IMZ B 110 |
| Chain | Residue |
| B | LEU54 |
| B | LEU54 |
| B | GLY58 |
| B | MET62 |
| B | GLN72 |
| B | HIS73 |
| B | VAL93 |
| B | HIS96 |
| B | HIS96 |
| B | TYR100 |
| B | IMZ111 |
| B | HOH120 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE IMZ C 110 |
| Chain | Residue |
| A | LEU54 |
| A | HIS96 |
| A | TYR100 |
| A | IMZ110 |
| A | IMZ111 |
| C | HOH9 |
| C | LEU54 |
| C | GLY58 |
| C | MET62 |
| C | GLN72 |
| C | HIS73 |
| C | VAL93 |
| C | HIS96 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE IMZ A 111 |
| Chain | Residue |
| A | HOH8 |
| A | HOH13 |
| A | HOH22 |
| A | THR26 |
| A | MET50 |
| A | TYR100 |
| B | THR26 |
| B | IMZ111 |
| C | GLU69 |
| C | IMZ110 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE IMZ B 111 |
| Chain | Residue |
| A | HOH22 |
| A | THR26 |
| A | IMZ111 |
| B | THR26 |
| B | MET50 |
| B | GLU69 |
| B | LYS70 |
| B | GLN72 |
| B | TYR100 |
| B | TYR104 |
| B | IMZ110 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 249 |
| Details | Domain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]} |
