Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 400 |
| Chain | Residue |
| A | DEO1 |
| A | HIS218 |
| A | HIS222 |
| A | HIS228 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | HIS168 |
| A | ASP170 |
| A | HIS183 |
| A | HIS196 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | GLY176 |
| A | GLY178 |
| A | ILE180 |
| A | ASP198 |
| A | GLU201 |
| A | ASP175 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | ASP158 |
| A | GLY190 |
| A | GLY192 |
| A | ASP194 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 404 |
| Chain | Residue |
| A | ASP124 |
| A | GLU199 |
| A | GLU201 |
| A | HOH497 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 500 |
| Chain | Residue |
| B | DEO1 |
| B | HIS218 |
| B | HIS222 |
| B | HIS228 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 501 |
| Chain | Residue |
| B | HIS168 |
| B | ASP170 |
| B | HIS183 |
| B | HIS196 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 502 |
| Chain | Residue |
| B | ASP175 |
| B | GLY176 |
| B | GLY178 |
| B | ILE180 |
| B | ASP198 |
| B | GLU201 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 503 |
| Chain | Residue |
| B | ASP158 |
| B | GLY190 |
| B | GLY192 |
| B | ASP194 |
| B | HOH591 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 504 |
| Chain | Residue |
| B | ASP124 |
| B | GLU199 |
| B | GLU201 |
| B | HOH565 |
| site_id | BC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE DEO A 1 |
| Chain | Residue |
| A | LEU181 |
| A | ALA182 |
| A | HIS183 |
| A | ALA184 |
| A | HIS218 |
| A | GLU219 |
| A | HIS222 |
| A | HIS228 |
| A | VAL235 |
| A | PHE237 |
| A | PRO238 |
| A | THR239 |
| A | TYR240 |
| A | LYS241 |
| A | PHE248 |
| A | ZN400 |
| A | HOH427 |
| A | HOH430 |
| site_id | BC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE DEO B 1 |
| Chain | Residue |
| B | LEU181 |
| B | ALA182 |
| B | HIS183 |
| B | ALA184 |
| B | HIS218 |
| B | GLU219 |
| B | HIS222 |
| B | HIS228 |
| B | VAL235 |
| B | PHE237 |
| B | PRO238 |
| B | THR239 |
| B | TYR240 |
| B | LYS241 |
| B | PHE248 |
| B | ZN500 |
| B | HOH508 |
| B | HOH513 |
| B | HOH529 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TAVHEIGHSL |
| Chain | Residue | Details |
| A | THR215-LEU224 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | GLU219 | |
| B | GLU219 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP124 | |
| A | ASP175 | |
| A | GLY176 | |
| A | GLY178 | |
| A | ILE180 | |
| A | HIS183 | |
| A | GLY190 | |
| A | GLY192 | |
| A | ASP194 | |
| A | HIS196 | |
| A | ASP198 | |
| A | GLU199 | |
| A | GLU201 | |
| A | HIS218 | |
| A | HIS222 | |
| A | HIS228 | |
| B | ASP124 | |
| B | ASP158 | |
| B | HIS168 | |
| B | ASP170 | |
| B | ASP175 | |
| B | GLY176 | |
| B | GLY178 | |
| B | ILE180 | |
| B | HIS183 | |
| B | GLY190 | |
| B | GLY192 | |
| B | ASP194 | |
| B | HIS196 | |
| B | ASP198 | |
| B | GLU199 | |
| B | GLU201 | |
| B | HIS218 | |
| B | HIS222 | |
| B | HIS228 | |
| A | ASP158 | |
| A | HIS168 | |
| A | ASP170 | |
