1QKI

X-RAY STRUCTURE OF HUMAN GLUCOSE 6-PHOSPHATE DEHYDROGENASE (VARIANT CANTON R459L) COMPLEXED WITH STRUCTURAL NADP+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
A	0005515	molecular_function	protein binding
A	0005536	molecular_function	D-glucose binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006006	biological_process	glucose metabolic process
A	0006098	biological_process	pentose-phosphate shunt
A	0006629	biological_process	lipid metabolic process
A	0006695	biological_process	cholesterol biosynthetic process
A	0006739	biological_process	NADP+ metabolic process
A	0006749	biological_process	glutathione metabolic process
A	0009051	biological_process	pentose-phosphate shunt, oxidative branch
A	0009898	cellular_component	cytoplasmic side of plasma membrane
A	0010041	biological_process	response to iron(III) ion
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0019322	biological_process	pentose biosynthetic process
A	0021762	biological_process	substantia nigra development
A	0030246	molecular_function	carbohydrate binding
A	0032094	biological_process	response to food
A	0034599	biological_process	cellular response to oxidative stress
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0043249	biological_process	erythrocyte maturation
A	0043523	biological_process	regulation of neuron apoptotic process
A	0045471	biological_process	response to ethanol
A	0046390	biological_process	ribose phosphate biosynthetic process
A	0050661	molecular_function	NADP binding
A	0051156	biological_process	glucose 6-phosphate metabolic process
A	0061052	biological_process	negative regulation of cell growth involved in cardiac muscle cell development
A	0070062	cellular_component	extracellular exosome
A	1904879	biological_process	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
A	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
B	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
B	0005515	molecular_function	protein binding
B	0005536	molecular_function	D-glucose binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006006	biological_process	glucose metabolic process
B	0006098	biological_process	pentose-phosphate shunt
B	0006629	biological_process	lipid metabolic process
B	0006695	biological_process	cholesterol biosynthetic process
B	0006739	biological_process	NADP+ metabolic process
B	0006749	biological_process	glutathione metabolic process
B	0009051	biological_process	pentose-phosphate shunt, oxidative branch
B	0009898	cellular_component	cytoplasmic side of plasma membrane
B	0010041	biological_process	response to iron(III) ion
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
B	0019322	biological_process	pentose biosynthetic process
B	0021762	biological_process	substantia nigra development
B	0030246	molecular_function	carbohydrate binding
B	0032094	biological_process	response to food
B	0034599	biological_process	cellular response to oxidative stress
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0043249	biological_process	erythrocyte maturation
B	0043523	biological_process	regulation of neuron apoptotic process
B	0045471	biological_process	response to ethanol
B	0046390	biological_process	ribose phosphate biosynthetic process
B	0050661	molecular_function	NADP binding
B	0051156	biological_process	glucose 6-phosphate metabolic process
B	0061052	biological_process	negative regulation of cell growth involved in cardiac muscle cell development
B	0070062	cellular_component	extracellular exosome
B	1904879	biological_process	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
B	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
C	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
C	0005515	molecular_function	protein binding
C	0005536	molecular_function	D-glucose binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006006	biological_process	glucose metabolic process
C	0006098	biological_process	pentose-phosphate shunt
C	0006629	biological_process	lipid metabolic process
C	0006695	biological_process	cholesterol biosynthetic process
C	0006739	biological_process	NADP+ metabolic process
C	0006749	biological_process	glutathione metabolic process
C	0009051	biological_process	pentose-phosphate shunt, oxidative branch
C	0009898	cellular_component	cytoplasmic side of plasma membrane
C	0010041	biological_process	response to iron(III) ion
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
C	0019322	biological_process	pentose biosynthetic process
C	0021762	biological_process	substantia nigra development
C	0030246	molecular_function	carbohydrate binding
C	0032094	biological_process	response to food
C	0034599	biological_process	cellular response to oxidative stress
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0043249	biological_process	erythrocyte maturation
C	0043523	biological_process	regulation of neuron apoptotic process
C	0045471	biological_process	response to ethanol
C	0046390	biological_process	ribose phosphate biosynthetic process
C	0050661	molecular_function	NADP binding
C	0051156	biological_process	glucose 6-phosphate metabolic process
C	0061052	biological_process	negative regulation of cell growth involved in cardiac muscle cell development
C	0070062	cellular_component	extracellular exosome
C	1904879	biological_process	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
C	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
D	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
D	0005515	molecular_function	protein binding
D	0005536	molecular_function	D-glucose binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006006	biological_process	glucose metabolic process
D	0006098	biological_process	pentose-phosphate shunt
D	0006629	biological_process	lipid metabolic process
D	0006695	biological_process	cholesterol biosynthetic process
D	0006739	biological_process	NADP+ metabolic process
D	0006749	biological_process	glutathione metabolic process
D	0009051	biological_process	pentose-phosphate shunt, oxidative branch
D	0009898	cellular_component	cytoplasmic side of plasma membrane
D	0010041	biological_process	response to iron(III) ion
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
D	0019322	biological_process	pentose biosynthetic process
D	0021762	biological_process	substantia nigra development
D	0030246	molecular_function	carbohydrate binding
D	0032094	biological_process	response to food
D	0034599	biological_process	cellular response to oxidative stress
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0043249	biological_process	erythrocyte maturation
D	0043523	biological_process	regulation of neuron apoptotic process
D	0045471	biological_process	response to ethanol
D	0046390	biological_process	ribose phosphate biosynthetic process
D	0050661	molecular_function	NADP binding
D	0051156	biological_process	glucose 6-phosphate metabolic process
D	0061052	biological_process	negative regulation of cell growth involved in cardiac muscle cell development
D	0070062	cellular_component	extracellular exosome
D	1904879	biological_process	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
D	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
E	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
E	0005515	molecular_function	protein binding
E	0005536	molecular_function	D-glucose binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006006	biological_process	glucose metabolic process
E	0006098	biological_process	pentose-phosphate shunt
E	0006629	biological_process	lipid metabolic process
E	0006695	biological_process	cholesterol biosynthetic process
E	0006739	biological_process	NADP+ metabolic process
E	0006749	biological_process	glutathione metabolic process
E	0009051	biological_process	pentose-phosphate shunt, oxidative branch
E	0009898	cellular_component	cytoplasmic side of plasma membrane
E	0010041	biological_process	response to iron(III) ion
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
E	0019322	biological_process	pentose biosynthetic process
E	0021762	biological_process	substantia nigra development
E	0030246	molecular_function	carbohydrate binding
E	0032094	biological_process	response to food
E	0034599	biological_process	cellular response to oxidative stress
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0043249	biological_process	erythrocyte maturation
E	0043523	biological_process	regulation of neuron apoptotic process
E	0045471	biological_process	response to ethanol
E	0046390	biological_process	ribose phosphate biosynthetic process
E	0050661	molecular_function	NADP binding
E	0051156	biological_process	glucose 6-phosphate metabolic process
E	0061052	biological_process	negative regulation of cell growth involved in cardiac muscle cell development
E	0070062	cellular_component	extracellular exosome
E	1904879	biological_process	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
E	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
F	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
F	0005515	molecular_function	protein binding
F	0005536	molecular_function	D-glucose binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006006	biological_process	glucose metabolic process
F	0006098	biological_process	pentose-phosphate shunt
F	0006629	biological_process	lipid metabolic process
F	0006695	biological_process	cholesterol biosynthetic process
F	0006739	biological_process	NADP+ metabolic process
F	0006749	biological_process	glutathione metabolic process
F	0009051	biological_process	pentose-phosphate shunt, oxidative branch
F	0009898	cellular_component	cytoplasmic side of plasma membrane
F	0010041	biological_process	response to iron(III) ion
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
F	0019322	biological_process	pentose biosynthetic process
F	0021762	biological_process	substantia nigra development
F	0030246	molecular_function	carbohydrate binding
F	0032094	biological_process	response to food
F	0034599	biological_process	cellular response to oxidative stress
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0043249	biological_process	erythrocyte maturation
F	0043523	biological_process	regulation of neuron apoptotic process
F	0045471	biological_process	response to ethanol
F	0046390	biological_process	ribose phosphate biosynthetic process
F	0050661	molecular_function	NADP binding
F	0051156	biological_process	glucose 6-phosphate metabolic process
F	0061052	biological_process	negative regulation of cell growth involved in cardiac muscle cell development
F	0070062	cellular_component	extracellular exosome
F	1904879	biological_process	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
F	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
G	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
G	0005515	molecular_function	protein binding
G	0005536	molecular_function	D-glucose binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006006	biological_process	glucose metabolic process
G	0006098	biological_process	pentose-phosphate shunt
G	0006629	biological_process	lipid metabolic process
G	0006695	biological_process	cholesterol biosynthetic process
G	0006739	biological_process	NADP+ metabolic process
G	0006749	biological_process	glutathione metabolic process
G	0009051	biological_process	pentose-phosphate shunt, oxidative branch
G	0009898	cellular_component	cytoplasmic side of plasma membrane
G	0010041	biological_process	response to iron(III) ion
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
G	0019322	biological_process	pentose biosynthetic process
G	0021762	biological_process	substantia nigra development
G	0030246	molecular_function	carbohydrate binding
G	0032094	biological_process	response to food
G	0034599	biological_process	cellular response to oxidative stress
G	0042802	molecular_function	identical protein binding
G	0042803	molecular_function	protein homodimerization activity
G	0043249	biological_process	erythrocyte maturation
G	0043523	biological_process	regulation of neuron apoptotic process
G	0045471	biological_process	response to ethanol
G	0046390	biological_process	ribose phosphate biosynthetic process
G	0050661	molecular_function	NADP binding
G	0051156	biological_process	glucose 6-phosphate metabolic process
G	0061052	biological_process	negative regulation of cell growth involved in cardiac muscle cell development
G	0070062	cellular_component	extracellular exosome
G	1904879	biological_process	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
G	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
H	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
H	0005515	molecular_function	protein binding
H	0005536	molecular_function	D-glucose binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006006	biological_process	glucose metabolic process
H	0006098	biological_process	pentose-phosphate shunt
H	0006629	biological_process	lipid metabolic process
H	0006695	biological_process	cholesterol biosynthetic process
H	0006739	biological_process	NADP+ metabolic process
H	0006749	biological_process	glutathione metabolic process
H	0009051	biological_process	pentose-phosphate shunt, oxidative branch
H	0009898	cellular_component	cytoplasmic side of plasma membrane
H	0010041	biological_process	response to iron(III) ion
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
H	0019322	biological_process	pentose biosynthetic process
H	0021762	biological_process	substantia nigra development
H	0030246	molecular_function	carbohydrate binding
H	0032094	biological_process	response to food
H	0034599	biological_process	cellular response to oxidative stress
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0043249	biological_process	erythrocyte maturation
H	0043523	biological_process	regulation of neuron apoptotic process
H	0045471	biological_process	response to ethanol
H	0046390	biological_process	ribose phosphate biosynthetic process
H	0050661	molecular_function	NADP binding
H	0051156	biological_process	glucose 6-phosphate metabolic process
H	0061052	biological_process	negative regulation of cell growth involved in cardiac muscle cell development
H	0070062	cellular_component	extracellular exosome
H	1904879	biological_process	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
H	2000378	biological_process	negative regulation of reactive oxygen species metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE NAP A 800

Chain	Residue
A	LYS238
A	ASP493
A	MET496
A	PHE501
A	TYR503
A	TRP509
A	ARG357
A	LYS366
A	ARG370
A	ARG393
A	TYR401
A	ASP421
A	THR423
A	ARG487

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOA A 900

Chain	Residue
A	LYS47
A	HIS201
A	LYS205

---

site_id	AC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE NAP B 800

Chain	Residue
B	LYS238
B	ARG357
B	GLU364
B	LYS366
B	ARG370
B	ARG393
B	TYR401
B	LYS403
B	ASP421
B	THR423
B	ARG487
B	ASP493
B	TYR503
B	TRP509

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOA B 900

Chain	Residue
B	TYR202
B	LYS205

---

site_id	AC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE NAP C 800

Chain	Residue
C	LYS238
C	ARG357
C	GLU364
C	LYS366
C	ARG370
C	ARG393
C	ALA399
C	TYR401
C	LYS403
C	ASP421
C	THR423
C	ARG487
C	ASP493
C	MET496
C	TYR503
C	TRP509

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOA C 900

Chain	Residue
C	TYR202
C	LYS205
C	ARG365

---

site_id	AC7
Number of Residues	15
Details	BINDING SITE FOR RESIDUE NAP D 800

Chain	Residue
D	LYS238
D	ARG357
D	GLU364
D	LYS366
D	ARG370
D	ARG393
D	TYR401
D	LYS403
D	ASP421
D	THR423
D	ARG487
D	ASP493
D	MET496
D	TYR503
D	TRP509

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOA D 900

Chain	Residue
D	LYS47
D	HIS201
D	TYR202
D	LYS205

---

site_id	AC9
Number of Residues	16
Details	BINDING SITE FOR RESIDUE NAP E 800

Chain	Residue
E	LYS238
E	ARG357
E	GLU364
E	LYS366
E	ARG370
E	ARG393
E	TYR401
E	LYS403
E	ASP421
E	THR423
E	ARG487
E	ASP493
E	MET496
E	TYR503
E	TYR507
E	TRP509

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOA E 900

Chain	Residue
E	HIS201
E	TYR202
E	ARG365
E	HOH2011

---

site_id	BC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE NAP F 800

Chain	Residue
F	THR423
F	ARG487
F	ASP493
F	PHE501
F	TYR503
F	TYR507
F	TRP509
F	LYS238
F	ARG357
F	LYS366
F	ARG370
F	ARG393
F	TYR401
F	LYS403
F	ASP421

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOA F 900

Chain	Residue
F	LYS47
F	HIS201
F	LYS205

---

site_id	BC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE NAP G 800

Chain	Residue
G	LYS238
G	ARG357
G	LYS366
G	ARG370
G	ARG393
G	TYR401
G	LYS403
G	ASP421
G	THR423
G	ARG487
G	ASP493
G	MET496
G	TYR503
G	TRP509

---

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOA G 900

Chain	Residue
G	HIS201
G	ARG365

---

site_id	BC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE NAP H 800

Chain	Residue
H	LYS238
H	ARG357
H	GLU364
H	LYS366
H	ARG370
H	ARG393
H	TYR401
H	LYS403
H	ASP421
H	THR423
H	ARG487
H	TYR503
H	TYR507
H	TRP509
H	HOH2008

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOA H 900

Chain	Residue
H	HIS201
H	LYS205
H	GLN395
H	ASP435

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL B 1101

Chain	Residue
B	ASP375
D	ARG227

---

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 1102

Chain	Residue
B	ARG227
B	ASP350
D	HIS374
D	ASP375

---

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL C 1103

Chain	Residue
A	ASP375
C	ARG227

---

site_id	CC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL G 1104

Chain	Residue
G	ARG227

---

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL E 1105

Chain	Residue
E	ARG227
G	ASP375
G	VAL376
G	ALA377

---

Functional Information from PROSITE/UniProt

site_id	PS00069
Number of Residues	7
Details	G6P_DEHYDROGENASE Glucose-6-phosphate dehydrogenase active site. DHYLGKE

Chain	Residue	Details
A	ASP200-GLU206

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P11411","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	168
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10745013","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15858258","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QKI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BH9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15858258","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BH9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15858258","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BHL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	24
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"24769394","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	5
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1dpg

Chain	Residue	Details
A	ASP200
A	HIS263

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1dpg

Chain	Residue	Details
B	ASP200
B	HIS263

---

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1dpg

Chain	Residue	Details
C	ASP200
C	HIS263

---

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1dpg

Chain	Residue	Details
D	ASP200
D	HIS263

---

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1dpg

Chain	Residue	Details
E	ASP200
E	HIS263

---

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1dpg

Chain	Residue	Details
F	ASP200
F	HIS263

---

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1dpg

Chain	Residue	Details
G	ASP200
G	HIS263

---

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1dpg

Chain	Residue	Details
H	ASP200
H	HIS263

---