1QKI
X-RAY STRUCTURE OF HUMAN GLUCOSE 6-PHOSPHATE DEHYDROGENASE (VARIANT CANTON R459L) COMPLEXED WITH STRUCTURAL NADP+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE | polymer | 514 | 59167.4 | 8 | UniProt (P11413) Pfam (PF00479) Pfam (PF02781) | HOMO SAPIENS (HUMAN) | G6PD |
| 2 | BA, I, K, O, R... (H, A, B, C, D...) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 8 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010) | |||
| 3 | CA, J, L, P, S... (H, A, B, C, D...) | GLYCOLIC ACID | non-polymer | 76.1 | 8 | Chemie (GOA) PubChem (757) | |||
| 4 | AA, M, N, Q, V (G, B, C, E) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) PubChem (753) | |||
| 5 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 2 - 515 (UniProt: P11413)
| PDB | External Database | Details |
|---|---|---|
| Leu 459 | Arg 458 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 473338.9 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 7016.1 | |
| All* | Total formula weight | 480355.1 |
