1NL0

Crystal structure of human factor IX Gla domain in complex of an inhibitory antibody, 10C12

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0005509	molecular_function	calcium ion binding
G	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA G 901

Chain	Residue
G	CGU26
G	CGU30

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA G 902

Chain	Residue
G	CGU8
G	CGU27
G	CGU30
G	HOH921

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA G 903

Chain	Residue
G	CGU30
G	HOH917
G	CGU8
G	CGU17
G	CGU27

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA G 904

Chain	Residue
G	TYR1
G	ASN2
G	CGU7
G	CGU8
G	CGU17
G	CGU27

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA G 905

Chain	Residue
G	TYR1
G	CGU7
G	CGU17
G	CGU21
G	HOH912

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA G 907

Chain	Residue
G	CGU15
G	CGU20

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site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 L 211

Chain	Residue
L	SER80
L	GLN109
L	TYR141
L	LYS167
L	HOH212

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Functional Information from PROSITE/UniProt

site_id	PS00011
Number of Residues	26
Details	GLA_1 Vitamin K-dependent carboxylation domain. EcmEEkCsfeearEvfentertte.FW

Chain	Residue	Details
G	CGU17-TRP42

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site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14722079","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NL0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"description":"via 4-carboxyglutamate","evidences":[{"source":"PubMed","id":"14722079","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1NL0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"4-carboxyglutamate","evidences":[{"source":"UniProtKB","id":"P00741","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00463","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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