1NHZ
Crystal Structure of the Antagonist Form of Glucocorticoid Receptor
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 486 A 800 |
| Chain | Residue |
| A | HOH126 |
| A | PHE623 |
| A | GLN642 |
| A | MET646 |
| A | LEU732 |
| A | PHE740 |
| A | MET560 |
| A | LEU563 |
| A | GLN570 |
| A | TRP600 |
| A | MET601 |
| A | MET604 |
| A | LEU608 |
| A | ARG611 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HEZ A 901 |
| Chain | Residue |
| A | HOH49 |
| A | HOH99 |
| A | PRO541 |
| A | GLU542 |
| A | LEU544 |
| A | GLN570 |
| A | TRP577 |
| A | LYS667 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE HEZ A 902 |
| Chain | Residue |
| A | HOH3 |
| A | HOH119 |
| A | GLN597 |
| A | TYR598 |
| A | SER599 |
| A | TRP600 |
| A | MET601 |
| A | SER674 |
| A | LEU733 |
| A | ILE769 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HEZ A 903 |
| Chain | Residue |
| A | HOH6 |
| A | HIS588 |
| A | HIS645 |
| A | TYR648 |
| A | GLU727 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 165 |
| Details | Region: {"description":"Interaction with CRY1","evidences":[{"source":"PubMed","id":"22170608","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"12144530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
