1LOA

THREE-DIMENSIONAL STRUCTURES OF COMPLEXES OF LATHYRUS OCHRUS ISOLECTIN I WITH GLUCOSE AND MANNOSE: FINE SPECIFICITY OF THE MONOSACCHARIDE-BINDING SITE

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Functional Information from GO Data

ChainGOidnamespacecontents
B0005537molecular_functionmannose binding
D0005537molecular_functionmannose binding
F0005537molecular_functionmannose binding
H0005537molecular_functionmannose binding
A0005537molecular_functionmannose binding
A0046872molecular_functionmetal ion binding
C0005537molecular_functionmannose binding
C0046872molecular_functionmetal ion binding
E0005537molecular_functionmannose binding
E0046872molecular_functionmetal ion binding
G0005537molecular_functionmannose binding
G0046872molecular_functionmetal ion binding
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC19BINDING SITE FOR RESIDUE GYP A 182
ChainResidue
AALA80
AASP81
AGLY98
AGLY99
APHE123
AASN125
BGLY29
BALA30
BGLU31

AC29BINDING SITE FOR RESIDUE GYP C 182
ChainResidue
CALA80
CASP81
CGLY99
CPHE123
CASN125
CHOH518
DGLY29
DALA30
DGLU31

AC39BINDING SITE FOR RESIDUE GYP E 182
ChainResidue
EALA80
EASP81
EGLY98
EGLY99
EPHE123
EASN125
FGLY29
FALA30
FGLU31

AC49BINDING SITE FOR RESIDUE GYP G 182
ChainResidue
GALA80
GASP81
GGLY98
GGLY99
GPHE123
GASN125
HGLY29
HALA30
HGLU31

AC56BINDING SITE FOR RESIDUE CA A 228
ChainResidue
AASP121
APHE123
AASN125
AASP129
AHOH268
AHOH269

AC66BINDING SITE FOR RESIDUE MN A 229
ChainResidue
AGLU119
AASP121
AASP129
AHIS136
AHOH270
AHOH276

AC76BINDING SITE FOR RESIDUE CA C 458
ChainResidue
CASP121
CPHE123
CASN125
CASP129
CHOH490
CHOH491

AC87BINDING SITE FOR RESIDUE MN C 459
ChainResidue
CGLU119
CASP121
CASP129
CHIS136
CHOH471
CHOH492
CHOH493

AC97BINDING SITE FOR RESIDUE CA E 688
ChainResidue
EASP81
EASP121
EPHE123
EASN125
EASP129
EHOH713
EHOH714

BC14BINDING SITE FOR RESIDUE MN F 689
ChainResidue
EALA153
EHOH739
FTHR2
FTYR4

BC26BINDING SITE FOR RESIDUE CA G 918
ChainResidue
GASP121
GPHE123
GASN125
GASP129
GHOH946
GHOH947

BC36BINDING SITE FOR RESIDUE MN G 919
ChainResidue
GGLU119
GASP121
GASP129
GHIS136
GHOH948
GHOH949

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
GYP_1loa_A_18211METHYL-ALPHA-D-GLUCOPYRANOSIDE binding site
ChainResidueligand
AALA80-ASP81GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
AGLY97-GLY99GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
APHE123GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
AASN125GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
BTHR28-GLU31GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE

GYP_1loa_C_18212METHYL-ALPHA-D-GLUCOPYRANOSIDE binding site
ChainResidueligand
CALA80-ASP81GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
CGLY97-TYR100GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
CPHE123GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
CASN125GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
DTHR28-GLU31GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE

GYP_1loa_E_18210METHYL-ALPHA-D-GLUCOPYRANOSIDE binding site
ChainResidueligand
EALA80-ASP81GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
EGLY98-GLY99GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
EPHE123GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
EASN125GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
FTHR28-GLU31GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE

GYP_1loa_G_18212METHYL-ALPHA-D-GLUCOPYRANOSIDE binding site
ChainResidueligand
GALA80-ASP81GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
GGLY97-TYR100GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
GPHE123GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
GASN125GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE
HTHR28-GLU31GYP: METHYL-ALPHA-D-GLUCOPYRANOSIDE

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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
PS0030840Legume lectins alpha-chain signature. [LIV]-{LA}-[EDQ]-[FYWKR]-V-{VF}-[LIVF]-G-[LF]-[ST]
ChainResidueDetails
BVAL16-SER25
DVAL16-SER25
FVAL16-SER25
HVAL16-SER25

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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI13Calcium
ChainResidueDetails
AASP121
AASN125
AASP129

SWS_FT_FI24Manganese
ChainResidueDetails
AGLU119
AASP121
AASP129
AHIS136

SWS_FT_FI31Calcium; via carbonyl oxygen
ChainResidueDetails
APHE123

SWS_FT_FI43Calcium
ChainResidueDetails
CASP121
CASN125
CASP129

SWS_FT_FI54Manganese
ChainResidueDetails
CGLU119
CASP121
CASP129
CHIS136

SWS_FT_FI61Calcium; via carbonyl oxygen
ChainResidueDetails
CPHE123

SWS_FT_FI73Calcium
ChainResidueDetails
EASP121
EASN125
EASP129

SWS_FT_FI84Manganese
ChainResidueDetails
EGLU119
EASP121
EASP129
EHIS136

SWS_FT_FI91Calcium; via carbonyl oxygen
ChainResidueDetails
EPHE123

SWS_FT_FI103Calcium
ChainResidueDetails
GASP121
GASN125
GASP129

SWS_FT_FI114Manganese
ChainResidueDetails
GGLU119
GASP121
GASP129
GHIS136

SWS_FT_FI121Calcium; via carbonyl oxygen
ChainResidueDetails
GPHE123

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Catalytic Information from CSA

site_idNumber of ResiduesDetails