1KCQ

Human Gelsolin Domain 2 with a Cd2+ bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0051015	molecular_function	actin filament binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 262

Chain	Residue
A	GLU258
A	GLU258
A	HOH273
A	HOH273
A	HOH358

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 263

Chain	Residue
A	HOH267
A	HOH268
A	GLY186
A	ASP187
A	GLU209
A	ASP259

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 264

Chain	Residue
A	GLU175
A	GLU175
A	HOH270
A	HOH270

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 265

Chain	Residue
A	HIS232
A	HOH355
A	HOH360
A	HOH374

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	72
Details	Repeat: {"description":"Gelsolin-like 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	38
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	15
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19666512","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3FFK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---