1J2J

Crystal structure of GGA1 GAT N-terminal region in complex with ARF1 GTP form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0002090	biological_process	regulation of receptor internalization
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005770	cellular_component	late endosome
A	0005778	cellular_component	peroxisomal membrane
A	0005794	cellular_component	Golgi apparatus
A	0005802	cellular_component	trans-Golgi network
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006878	biological_process	intracellular copper ion homeostasis
A	0006886	biological_process	intracellular protein transport
A	0007015	biological_process	actin filament organization
A	0012505	cellular_component	endomembrane system
A	0014069	cellular_component	postsynaptic density
A	0015031	biological_process	protein transport
A	0016192	biological_process	vesicle-mediated transport
A	0016787	molecular_function	hydrolase activity
A	0019003	molecular_function	GDP binding
A	0019904	molecular_function	protein domain specific binding
A	0030017	cellular_component	sarcomere
A	0030137	cellular_component	COPI-coated vesicle
A	0031252	cellular_component	cell leading edge
A	0032991	cellular_component	protein-containing complex
A	0034315	biological_process	regulation of Arp2/3 complex-mediated actin nucleation
A	0034379	biological_process	very-low-density lipoprotein particle assembly
A	0043005	cellular_component	neuron projection
A	0045202	cellular_component	synapse
A	0045807	biological_process	positive regulation of endocytosis
A	0045956	biological_process	positive regulation of calcium ion-dependent exocytosis
A	0050714	biological_process	positive regulation of protein secretion
A	0055108	biological_process	Golgi to transport vesicle transport
A	0060292	biological_process	long-term synaptic depression
A	0060999	biological_process	positive regulation of dendritic spine development
A	0070142	biological_process	synaptic vesicle budding
A	0097061	biological_process	dendritic spine organization
A	0097212	biological_process	lysosomal membrane organization
A	0098586	biological_process	cellular response to virus
A	0098974	biological_process	postsynaptic actin cytoskeleton organization
A	0098978	cellular_component	glutamatergic synapse
A	1902307	biological_process	positive regulation of sodium ion transmembrane transport
A	1902824	biological_process	positive regulation of late endosome to lysosome transport
A	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
A	1903725	biological_process	regulation of phospholipid metabolic process
A	1990386	biological_process	mitotic cleavage furrow ingression
A	1990583	molecular_function	phospholipase D activator activity
B	0005802	cellular_component	trans-Golgi network
B	0006886	biological_process	intracellular protein transport
B	0031267	molecular_function	small GTPase binding
B	0035091	molecular_function	phosphatidylinositol binding
B	0043130	molecular_function	ubiquitin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1002

Chain	Residue
A	THR31
A	THR48
A	GTP1001
A	HOH1021
A	HOH1022

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 1

Chain	Residue
A	TRP66

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 2

Chain	Residue
B	ARG180

---

site_id	AC4
Number of Residues	26
Details	BINDING SITE FOR RESIDUE GTP A 1001

Chain	Residue
A	ALA28
A	GLY29
A	LYS30
A	THR31
A	THR32
A	THR45
A	THR48
A	GLY69
A	GLY70
A	ASN126
A	LYS127
A	ASP129
A	LEU130
A	ALA160
A	MG1002
A	HOH1015
A	HOH1017
A	HOH1018
A	HOH1021
A	HOH1022
A	HOH1025
A	HOH1093
A	HOH1094
A	HOH1095
A	ASP26
A	ALA27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12679809","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1O3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2J59","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"1O3Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2J59","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	LEU71

---