1HPT
THREE-DIMENSIONAL STRUCTURE OF A RECOMBINANT VARIANT OF HUMAN PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004866 | molecular_function | endopeptidase inhibitor activity |
| A | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0030414 | molecular_function | peptidase inhibitor activity |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from PROSITE/UniProt
| site_id | PS00282 |
| Number of Residues | 23 |
| Details | KAZAL_1 Kazal serine protease inhibitors family signature. CtyeyRpvCgTdgdtYpneCvl.C |
| Chain | Residue | Details |
| A | CYS16-CYS38 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 53 |
| Details | Domain: {"description":"Kazal-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00798","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Reactive bond for trypsin","evidences":[{"source":"UniProtKB","id":"P09036","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00798","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Necessary for sperm binding","evidences":[{"source":"UniProtKB","id":"P09036","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
