Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016311 | biological_process | dephosphorylation |
| A | 0016791 | molecular_function | phosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE TLA A 1352 |
| Chain | Residue |
| A | ASP92 |
| A | HOH1439 |
| A | HIS93 |
| A | CYS124 |
| A | LYS125 |
| A | ALA126 |
| A | GLY129 |
| A | ARG130 |
| A | GLN171 |
| A | HOH1381 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. IHCkaGkgRTG |
| Chain | Residue | Details |
| A | ILE122-GLY132 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 171 |
| Details | Domain: {"description":"Phosphatase tensin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00590","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Region: {"description":"Required for interaction with NOP53","evidences":[{"source":"PubMed","id":"15355975","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00590","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"26166433","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by FRK","evidences":[{"source":"PubMed","id":"19345329","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 9593664, 10555148 |
| Chain | Residue | Details |
| A | ASP92 | |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 456 |
| Chain | Residue | Details |
| A | ASP92 | proton shuttle (general acid/base) |
| A | CYS124 | covalent catalysis |
| A | ARG130 | transition state stabiliser |
