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8WGR

Cryo-EM structure of inward-open state human norepinephrine transporter NET bound with antidepressant desipramine in KCl condition.

EM specimen
VitrificationYes
EM Data Collection
MicroscopeFEI TITAN KRIOS
Electron GunFIELD EMISSION GUN
Accelerating Voltage (kV)300
DetectorGATAN K3 (6k x 4k)
3D Reconstruction
MethodSINGLE PARTICLE
Resolution (Å)2.75
SoftwarecryoSPARC,PHENIX
SymmetryC1
CTF correctionNONE

238895

PDB entries from 2025-07-16

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