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8TZH

Structure of full-length LRRK2 bound to MLi-2 (I2020T mutant)

EM specimen
VitrificationYes
InstrumentFEI VITROBOT MARK IV
EM Data Collection
MicroscopeFEI TITAN KRIOS
Electron GunFIELD EMISSION GUN
Accelerating Voltage (kV)300
Cs (mm)2.7
DetectorFEI FALCON IV (4k x 4k)
3D Reconstruction
MethodSINGLE PARTICLE
Resolution (Å)3.9
Number of Particle220313
SoftwareTopaz,cryoSPARC,PHENIX,CTFFIND,UCSF ChimeraX
SymmetryC1
CTF correctionPHASE FLIPPING AND AMPLITUDE CORRECTION

227561

PDB entries from 2024-11-20

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