8P0M
Crystal structure of TEAD3 in complex with IAG933
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | SLS BEAMLINE X10SA |
Synchrotron site | SLS |
Beamline | X10SA |
Temperature [K] | 100 |
Detector technology | PIXEL |
Collection date | 2019-09-05 |
Detector | DECTRIS PILATUS 6M |
Wavelength(s) | 1.21421 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 65.503, 127.236, 155.536 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 98.480 - 1.961 |
R-factor | 0.215 |
Rwork | 0.214 |
R-free | 0.22830 |
Structure solution method | MOLECULAR REPLACEMENT |
RMSD bond length | 0.008 |
RMSD bond angle | 0.970 |
Data reduction software | autoPROC |
Data scaling software | STARANISO |
Phasing software | PHASER |
Refinement software | BUSTER (2.11.8) |
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 98.480 | 2.034 |
High resolution limit [Å] | 1.960 | 1.961 |
Rmerge | 0.130 | 1.596 |
Rmeas | 0.133 | 1.645 |
Number of reflections | 78842 | 3756 |
<I/σ(I)> | 17.5 | 1.9 |
Completeness [%] | 84.0 | |
Redundancy | 25 | |
CC(1/2) | 0.999 | 0.756 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, SITTING DROP | 7.5 | 294 | Hepes, Magnesium chloride hexahydrate, PEG monomethyl-ether 550 |