8P0M
Crystal structure of TEAD3 in complex with IAG933
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X10SA |
| Synchrotron site | SLS |
| Beamline | X10SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2019-09-05 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 1.21421 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 65.503, 127.236, 155.536 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 98.480 - 1.961 |
| R-factor | 0.215 |
| Rwork | 0.214 |
| R-free | 0.22830 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.008 |
| RMSD bond angle | 0.970 |
| Data reduction software | autoPROC |
| Data scaling software | STARANISO |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.8) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 98.480 | 2.034 |
| High resolution limit [Å] | 1.960 | 1.961 |
| Rmerge | 0.130 | 1.596 |
| Rmeas | 0.133 | 1.645 |
| Number of reflections | 78842 | 3756 |
| <I/σ(I)> | 17.5 | 1.9 |
| Completeness [%] | 84.0 | |
| Redundancy | 25 | |
| CC(1/2) | 0.999 | 0.756 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 7.5 | 294 | Hepes, Magnesium chloride hexahydrate, PEG monomethyl-ether 550 |
