7PHS
highly potent IL6 antagonistic antibody selected from a camelid immune phage display repertoire
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | ESRF BEAMLINE ID14-4 |
Synchrotron site | ESRF |
Beamline | ID14-4 |
Temperature [K] | 100 |
Detector technology | PIXEL |
Collection date | 2011-07-27 |
Detector | DECTRIS EIGER X 4M |
Wavelength(s) | 0.923 |
Spacegroup name | P 43 21 2 |
Unit cell lengths | 58.990, 58.990, 285.830 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 45.000 | 2.900 |
High resolution limit [Å] | 2.770 | 2.770 |
Rmerge | 0.110 | 0.860 |
Number of reflections | 13561 | 1635 |
<I/σ(I)> | 18.6 | 3.3 |
Completeness [%] | 98.4 | |
Redundancy | 8.6 | |
CC(1/2) | 0.990 | 0.830 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION | 4.5 | 293 | 30% PEG 8K, 0.2M Li2SO4, 0.1M acetate pH 4.5. |