7L7R

CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 19-ID
Synchrotron site	APS
Beamline	19-ID
Temperature [K]	100
Detector technology	CCD
Collection date	2019-08-01
Detector	ADSC QUANTUM 315
Wavelength(s)	0.979
Spacegroup name	P 21 21 21
Unit cell lengths	60.200, 95.179, 323.000
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	43.050 - 2.100
R-factor	0.22
Rwork	0.219
R-free	0.24350
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	5i19 1hez
RMSD bond length	0.006
RMSD bond angle	0.815
Data reduction software	MOSFLM
Data scaling software	Aimless
Phasing software	PHASER
Refinement software	PHENIX (1.19_4080)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	43.100	2.140
High resolution limit [Å]	2.100	2.100
Number of reflections	107701	5342
<I/σ(I)>	9.5
Completeness [%]	98.5
Redundancy	6.1
CC(1/2)	0.997	0.697

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION		293	0.1 M sodium citrate pH 5.6, 2% (v/v) MPD, 13.4% (w/v) PEG 8000