7L7R

CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0019049	biological_process	virus-mediated perturbation of host defense response
G	0044423	cellular_component	virion component

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Ctgd.CperCgctsstclHkewp.H

Chain	Residue	Details
G	CYS1165-HIS1187

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site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
B	TYR194-HIS200
A	TYR192-HIS198
D	TYR194-HIS200
C	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	SITE: Involved in fusion with the host membrane => ECO:0000269|PubMed:34793197

Chain	Residue	Details
G	TRP1199
G	MET1362
G	TRP1365
G	HIS1479
G	TRP1068
G	TRP1191
G	TRP1197

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:17197010

Chain	Residue	Details
G	ASN1054
G	ASN1563

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