7L7R
CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADI-36121 Fab light chain | polymer | 214 | 23416.9 | 1 | Homo sapiens | ||
| 2 | B (B) | ADI-36121 Fab heavy chain | polymer | 230 | 24663.8 | 1 | Homo sapiens | ||
| 3 | C (C) | ADI-37801 Fab light chain | polymer | 214 | 23473.1 | 1 | Homo sapiens | ||
| 4 | D (D) | ADI-37801 Fab heavy chain | polymer | 235 | 25039.0 | 1 | Homo sapiens | ||
| 5 | E (G) | Glycoprotein C | polymer | 547 | 60898.1 | 1 | UniProt (Q8JSZ3) Pfam (PF01561) Pfam (PF20682) | Crimean-Congo hemorrhagic fever virus (strain Nigeria/IbAr10200/1970) (CCHFV) | |
| 6 | F (N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 7 | G, H, I, J, K (A, B, C, D, G) | water | water | 18.0 | 396 | Chemie (HOH) |
Sequence modifications
G: 1041 - 1579 (UniProt: Q8JSZ3)
| PDB | External Database | Details |
|---|---|---|
| Gly 1580 | - | expression tag |
| Ser 1581 | - | expression tag |
| Leu 1582 | - | expression tag |
| Glu 1583 | - | expression tag |
| Val 1584 | - | expression tag |
| Leu 1585 | - | expression tag |
| Phe 1586 | - | expression tag |
| Gln 1587 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 157490.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| All* | Total formula weight | 158077.5 |
