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7L7R

CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AADI-36121 Fab light chainpolymer21423416.91Homo sapiens
2BADI-36121 Fab heavy chainpolymer23024663.81Homo sapiens
3CADI-37801 Fab light chainpolymer21423473.11Homo sapiens
4DADI-37801 Fab heavy chainpolymer23525039.01Homo sapiens
5GGlycoprotein Cpolymer54760898.11UniProt (Q8JSZ3)
Pfam (PF01561)
Pfam (PF20682)
In PDB
Crimean-Congo hemorrhagic fever virus (strain Nigeria/IbAr10200/1970) (CCHFV)
6Nbeta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G15407YE)
7waterwater18.0396Chemie (HOH)
Sequence modifications
G: 1041 - 1579 (UniProt: Q8JSZ3)
PDBExternal DatabaseDetails
Gly 1580-expression tag
Ser 1581-expression tag
Leu 1582-expression tag
Glu 1583-expression tag
Val 1584-expression tag
Leu 1585-expression tag
Phe 1586-expression tag
Gln 1587-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight157490.9
BranchedNumber of molecules1
Total formula weight586.5
All*Total formula weight158077.5
*Water molecules are not included.

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PDB entries from 2024-06-12

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