6UYC

Crystal structure of TEAD2 bound to Compound 2

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ALS BEAMLINE 5.0.2
Synchrotron site	ALS
Beamline	5.0.2
Temperature [K]	100
Detector technology	PIXEL
Collection date	2017-04-12
Detector	DECTRIS PILATUS3 6M
Wavelength(s)	1.00000
Spacegroup name	C 1 2 1
Unit cell lengths	123.422, 61.249, 80.206
Unit cell angles	90.00, 117.26, 90.00

Refinement procedure

Resolution	58.241 - 1.658
R-factor	0.1949
Rwork	0.194
R-free	0.21630
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	5emv
Data reduction software	ADDREF
Data scaling software	autoPROC
Phasing software	PHENIX
Refinement software	PHENIX (dev_3290)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	58.241	1.819
High resolution limit [Å]	1.658	1.661
Number of reflections	36599	1830
<I/σ(I)>	15.7
Completeness [%]	87.1
Redundancy	3.3
CC(1/2)	0.999	0.628

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	6.5	292	200 mM potassium/sodium tartrate pH 6.5 20% PEG 3350