5HLW
Crystal structure of c-Met mutant Y1230H in complex with compound 14
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | ESRF BEAMLINE ID23-1 |
Synchrotron site | ESRF |
Beamline | ID23-1 |
Temperature [K] | 100 |
Detector technology | CCD |
Collection date | 2009-08-04 |
Detector | ADSC QUANTUM 315 |
Wavelength(s) | 0.9765 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 43.320, 46.690, 156.960 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 34.840 - 1.970 |
RMSD bond length | 0.010 |
RMSD bond angle | 1.010 |
Data reduction software | MOSFLM |
Data scaling software | SCALA |
Phasing software | PHASER |
Refinement software | BUSTER (2.11.5) |
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 34.840 | 2.020 |
High resolution limit [Å] | 1.970 | 1.970 |
Rmerge | 0.235 | |
Number of reflections | 21753 | |
<I/σ(I)> | 8.8 | 3.4 |
Completeness [%] | 100.0 | 100 |
Redundancy | 4 | 3 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, HANGING DROP | 8 | 293 | Tris 100mM-MPD20%-pH8 |