5YZC
Crystal structure of the prefusion form of measles virus fusion protein in complex with a fusion inhibitor compound (AS-48)
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | PHOTON FACTORY BEAMLINE BL-1A |
| Synchrotron site | Photon Factory |
| Beamline | BL-1A |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2017-02-23 |
| Detector | DECTRIS EIGER X 4M |
| Wavelength(s) | 1.1 |
| Spacegroup name | I 21 3 |
| Unit cell lengths | 169.497, 169.497, 169.497 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 53.600 - 2.334 |
| R-factor | 0.1856 |
| Rwork | 0.184 |
| R-free | 0.22150 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 5yxw |
| RMSD bond length | 0.008 |
| RMSD bond angle | 0.937 |
| Data reduction software | XDS |
| Data scaling software | Aimless |
| Phasing software | PHENIX |
| Refinement software | PHENIX ((1.11_2567)) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 119.852 | 2.342 |
| High resolution limit [Å] | 2.334 | 2.334 |
| Number of reflections | 34515 | |
| <I/σ(I)> | 14.3 | |
| Completeness [%] | 100.0 | |
| Redundancy | 20.9 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 293 | sodium formate, glycerol, sodium acetate |
