5HFM
Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU MICROMAX-007 |
| Temperature [K] | 100 |
| Detector technology | IMAGE PLATE |
| Collection date | 2015-08-06 |
| Detector | RIGAKU RAXIS IV |
| Wavelength(s) | 1.5418 |
| Spacegroup name | P 1 |
| Unit cell lengths | 39.112, 39.076, 90.602 |
| Unit cell angles | 90.03, 89.98, 120.06 |
Refinement procedure
| Resolution | 33.850 - 2.298 |
| R-factor | 0.2029 |
| Rwork | 0.200 |
| R-free | 0.24670 |
| RMSD bond length | 0.003 |
| RMSD bond angle | 0.497 |
| Data reduction software | HKL-2000 |
| Data scaling software | HKL-2000 |
| Phasing software | PHASER |
| Refinement software | PHENIX (1.8.2_1309) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 33.900 |
| High resolution limit [Å] | 2.298 |
| Number of reflections | 18969 |
| <I/σ(I)> | 16.4 |
| Completeness [%] | 92.3 |
| Redundancy | 1.6 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 8.2 | 289 | 1.4 M Sodium Potassium Phosphate |
