4UXQ
FGFR4 in complex with Ponatinib
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | DIAMOND BEAMLINE I04-1 |
Synchrotron site | Diamond |
Beamline | I04-1 |
Temperature [K] | 100 |
Detector technology | PIXEL |
Detector | DECTRIS PILATUS 6M |
Spacegroup name | P 1 21 1 |
Unit cell lengths | 41.835, 58.371, 60.570 |
Unit cell angles | 90.00, 96.48, 90.00 |
Refinement procedure
Resolution | 20.000 - 1.850 |
R-factor | 0.2048 |
Rwork | 0.201 |
R-free | 0.26810 |
Structure solution method | OTHER |
Starting model (for MR) | NONE |
RMSD bond length | 0.010 |
RMSD bond angle | 1.120 |
Refinement software | BUSTER (2.11.5) |
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 30.000 | 1.950 |
High resolution limit [Å] | 1.850 | 1.850 |
Rmerge | 0.180 | 0.287 |
Number of reflections | 14141 | |
<I/σ(I)> | 7.3 | 2.6 |
Completeness [%] | 57.0 | 8 |
Redundancy | 4.6 | 2.6 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | 0.1MPCTP, PH4.5 0.1M (NH4)2SO4, 15% PEG3350 |