4DFN
Crystal structure of spleen tyrosine kinase complexed with an adamantylpyrazine inhibitor
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | SLS BEAMLINE X06SA |
Synchrotron site | SLS |
Beamline | X06SA |
Temperature [K] | 100 |
Detector technology | PILATUS 6M |
Collection date | 2009-04-09 |
Detector | DECTRIS |
Wavelength(s) | 1 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 40.295, 84.848, 90.996 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 62.060 - 2.480 |
R-factor | 0.222 |
Rwork | 0.217 |
R-free | 0.27340 |
Structure solution method | OTHER |
Starting model (for MR) | NONE |
RMSD bond length | 0.006 |
RMSD bond angle | 0.862 |
Data reduction software | XDS |
Data scaling software | XSCALE |
Refinement software | REFMAC (5.5.0088) |
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 62.060 | 2.640 |
High resolution limit [Å] | 2.480 | 2.480 |
Rmerge | 0.069 | 0.819 |
Number of reflections | 11590 | |
Completeness [%] | 99.4 | 97.2 |
Redundancy | 5.6 | 5.5 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 |