4C7K
11b-Hydroxysteroid Dehydrogenase Type I in complex with inhibitor
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU FR-E+ SUPERBRIGHT |
| Temperature [K] | 100 |
| Detector technology | IMAGE PLATE |
| Collection date | 2011-02-22 |
| Detector | RIGAKU HTC |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 99.330, 99.250, 99.940 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 49.630 - 1.910 |
| R-factor | 0.2424 |
| Rwork | 0.240 |
| R-free | 0.29050 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 4bb5 |
| RMSD bond length | 0.010 |
| RMSD bond angle | 1.120 |
| Data reduction software | XDS |
| Data scaling software | SCALA |
| Phasing software | MOLREP |
| Refinement software | BUSTER (2.11.5) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 49.630 | 1.960 |
| High resolution limit [Å] | 1.910 | 1.910 |
| Rmerge | 0.090 | 0.440 |
| Number of reflections | 74883 | |
| <I/σ(I)> | 20.4 | 4.9 |
| Completeness [%] | 96.1 | 87.9 |
| Redundancy | 7.1 | 6.2 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
