4P0V
Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 21-ID-F |
| Synchrotron site | APS |
| Beamline | 21-ID-F |
| Temperature [K] | 300 |
| Detector technology | CCD |
| Collection date | 2013-12-13 |
| Detector | MARMOSAIC 225 mm CCD |
| Wavelength(s) | 0.97872 |
| Spacegroup name | P 41 21 2 |
| Unit cell lengths | 112.143, 112.143, 67.053 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 79.300 - 2.400 |
| R-factor | 0.2062 |
| Rwork | 0.202 |
| R-free | 0.29250 |
| RMSD bond length | 0.014 |
| RMSD bond angle | 1.575 |
| Refinement software | REFMAC (5.8.0049) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 79.300 |
| High resolution limit [Å] | 2.400 |
| Number of reflections | 17015 |
| <I/σ(I)> | 29.78 |
| Completeness [%] | 98.5 |
| Redundancy | 8.1 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 5 | 293 | 1.2M sodium potassium phosphate, 25% glycerol |
