3SXR

Crystal structure of BMX non-receptor tyrosine kinase complex with dasatinib

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X06DA
Synchrotron site	SLS
Beamline	X06DA
Temperature [K]	100
Detector technology	CCD
Collection date	2008-09-27
Detector	MARMOSAIC 225 mm CCD
Spacegroup name	P 21 21 21
Unit cell lengths	58.680, 67.130, 169.290
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	48.220 - 2.400
R-factor	0.1892
Rwork	0.187
R-free	0.23110
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.010
RMSD bond angle	1.120
Data reduction software	XDS
Data scaling software	XSCALE
Phasing software	PHASER
Refinement software	BUSTER (2.11.1)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	50.000	2.540
High resolution limit [Å]	2.400	2.400
Rmerge	0.109	0.531
Number of reflections	26852
<I/σ(I)>	13.5	3
Completeness [%]	99.5	97.6
Redundancy	4.7	4.4

Crystallization Conditions

crystal ID	method	pH	temperature	details
1