2ZVA
Lyn Tyrosine Kinase Domain-Dasatinib complex
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU RUH3R |
| Temperature [K] | 100 |
| Wavelength(s) | 1.54180 |
| Spacegroup name | H 3 |
| Unit cell lengths | 127.378, 127.378, 55.619 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 33.370 - 2.600 |
| R-factor | 0.19935 |
| Rwork | 0.198 |
| R-free | 0.23111 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 1qpd |
| RMSD bond length | 0.007 |
| RMSD bond angle | 1.204 |
| Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 39.200 |
| High resolution limit [Å] | 2.600 |
| Number of reflections | 10106 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 7.5 | 277 | 23% polyethylene glycol 3350, 0.1M NaCl, 0.1M Na-Hepes pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K |
