2ZVA
Lyn Tyrosine Kinase Domain-Dasatinib complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase Lyn | polymer | 279 | 31810.6 | 1 | UniProt (P25911) Pfam (PF07714) | Mus musculus (mouse) | |
| 2 | B (A) | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | non-polymer | 488.0 | 1 | Chemie (1N1) | |||
| 3 | C (A) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A: 239 - 512 (UniProt: P25911)
| PDB | External Database | Details |
|---|---|---|
| Gly 234 | - | expression tag |
| Ala 235 | - | expression tag |
| Met 236 | - | expression tag |
| Asp 237 | - | expression tag |
| Pro 238 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31810.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 488.0 | |
| All* | Total formula weight | 32298.6 |
