2XD6
Hsp90 complexed with a resorcylic acid macrolactone.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | BRUKER AXS MICROSTAR |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2009-12-03 |
| Detector | BRUKER |
| Spacegroup name | P 43 2 2 |
| Unit cell lengths | 73.767, 73.767, 110.284 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 31.606 - 2.200 |
| R-factor | 0.1728 |
| Rwork | 0.170 |
| R-free | 0.22790 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 1ah6 |
| RMSD bond length | 0.007 |
| RMSD bond angle | 1.050 |
| Data reduction software | SAINT |
| Data scaling software | XPREP |
| Phasing software | PHASER |
| Refinement software | PHENIX ((PHENIX.REFINE)) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 35.000 | 2.300 |
| High resolution limit [Å] | 2.200 | 2.200 |
| Rmerge | 0.060 | 0.260 |
| Number of reflections | 16104 | |
| <I/σ(I)> | 18.9 | 4.7 |
| Completeness [%] | 99.8 | 99.8 |
| Redundancy | 6.6 | 4.7 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | 7 | pH 7 |
